Accession Protein name Subfamily Organism Kingdom Kinetically characterized substrates Highest efficiency substrate Structures
CTBP_ARATH - - Arabidopsis thaliana (thale cress) Eukaryotes - - -
O28495_ARCFU - - Archaeoglobus fulgidus DSM 4304 Archaea - - -
Q8G427_BIFLO - - Bifidobacterium longum NCC2705 Bacteria - - -
B1L3A6_KORCO - - Candidatus Korarchaeum cryptofilum Archaea - - -
Q5L308_GEOKA - - Geobacillus kaustophilus Bacteria - - -
B0JPW3_MICAN - - Nitrosopumilus maritimus Archaea - - -
Q8LN38_ORYSJ - - Oryza sativa japonica (Japanese rice) (RefSeq) Eukaryotes - - -
B7FWC8_PHATC - - Phaeodactylum tricornutum Eukaryotes - - -
Q2KBF2_RHIEC - - Rhizobium etli CFN 42 Bacteria - - -
bta:513131 CTBP1; C-terminal binding protein 1 CTBP Bos taurus (cow) Eukaryotes - - -
CTBP2_BOVIN CTBP2; C-terminal binding protein 2 CTBP Bos taurus (cow) Eukaryotes - - -
CTBP1_CAEEL ctbp-1; C-terminal-binding protein 1 CTBP Caenorhabditis elegans (nematode) Eukaryotes - - -
Q7ZU55_DANRE ctbp1, wu:fi43a11; C-terminal binding protein 1 CTBP Danio rerio (zebrafish) Eukaryotes - - -
Q5BU19_DANRE ctbp2a, ctbp2, fe05b01, wu:fb96g03, wu:fe05b01, wu:fk19e02; C-terminal binding protein 2a CTBP Danio rerio (zebrafish) Eukaryotes - - -
Q5BU17_DANRE ctbp2l; C-terminal binding protein 2, like CTBP Danio rerio (zebrafish) Eukaryotes - - -
Q1RLQ4_DANRE wu:fa96d06; zgc:136929 CTBP Danio rerio (zebrafish) Eukaryotes - - -
CTBP_DROME CtBP; C-terminal Binding Protein (EC:1.1.1.-) CTBP Drosophila melanogaster (fruit fly) Eukaryotes - - -
Q5ZMM8_CHICK C-terminal binding protein-like CTBP Gallus gallus (chicken) Eukaryotes - - -
Q5ZIZ6_CHICK CTBP1; C-terminal binding protein 1 CTBP Gallus gallus (chicken) Eukaryotes - - -
gga:423958 CTBP2; C-terminal binding protein 2 CTBP Gallus gallus (chicken) Eukaryotes - - -
CTBP1_HUMAN CTBP1, BARS; C-terminal binding protein 1 CTBP Homo sapiens (human) Eukaryotes 3-phosphohydroxypyruvate, 2-keto-D-gluconate, 2-ketovalerate, pyruvate, 2-ketoisocaproate, 2-ketoglutarate, 2-keto-4-methylthiobutyrate, phenylpyruvate, oxaloacetate, 2-ketocaproate, glyoxylate 2-keto-4-methylthiobutyrate PMID:17157814 4LCE (NAD, 4‑methylthio‑2‑oxobutyric acid) PMID:24657618
1MX3 (NAD, acetic acid) PMID:12419229
4U6Q (NAD, 2‑(hydroxyimino)‑3‑phenylpropanoic acid) PMID:25636004
4U6S (NAD, 3‑phenylpyruvic acid) PMID:25636004
CTBP2_HUMAN CTBP2; C-terminal binding protein 2 CTBP Homo sapiens (human) Eukaryotes 2-keto-4-methylthiobutyrate 2-keto-4-methylthiobutyrate - 2OME (NAD)
4LCJ (NAD, 4‑methylthio‑2‑oxobutyric acid) PMID:24657618
CTBP1_MOUSE Ctbp1, BARS, CtBP3/BARS, D4S115h, D5H4S115, D5H4S115E; C-terminal binding protein 1 CTBP Mus musculus (mouse) Eukaryotes - - -
CTBP2_MOUSE Ctbp2, AA407280, D7Ertd45e, Gtrgeo6, Ribeye; C-terminal binding protein 2 CTBP Mus musculus (mouse) Eukaryotes - - -
CTBP1_RAT C-terminal-binding protein 1 CTBP Rattus norvegicus Eukaryotes - - - 1HKU (NAD, formic acid) PMID:12805226
1HL3 (NAD) PMID:12805226
3GA0 (Formic acid) PMID:19351597
CTBP1_XENLA ctbp1, CtBP, ctbp1-A, xctbp1; C-terminal binding protein 1 CTBP Xenopus laevis (African clawed frog) Eukaryotes - - -
CTBP2_XENLA ctbp2, ctbp, ctbp-b; C-terminal binding protein 2 CTBP Xenopus laevis (African clawed frog) Eukaryotes - - -
Q5XHH5_XENLA uncharacterized LOC494997 CTBP Xenopus laevis (African clawed frog) Eukaryotes - - -
Q3M599_ANAVT D-isomer specific 2-hydroxyacid dehydrogenase (EC:1.1.1.26) DDH Anabaena variabilis Bacteria - - -
ang:ANI_1_1478134 An15g04440; hypothetical protein DDH Aspergillus niger Eukaryotes - - -
ang:ANI_1_642134 An15g04660; dehydrogenase DDH Aspergillus niger Eukaryotes - - -
Q5V4Z5_HALMA serA4; phosphoglycerate dehydrogenase (EC:1.1.1.95) DDH Haloarcula marismortui Archaea - - -
Q5UZP4_HALMA serA5; phosphoglycerate dehydrogenase (EC:1.1.1.95) DDH Haloarcula marismortui Archaea - - -
DDH_HALMT D-2-hydroxyacid dehydrogenase DDH Haloferax mediterranei Archaea pyruvate, 2-ketoisocaproate, 2-ketobutyrate, 2-keto-3-methylvalerate 2-ketobutyrate PMID:17049749 5MHA (NADPH, 2‑ketohexanoic acid, 2‑hydroxyhexanoic acid)
5MH5 (NADP, 2‑ketohexanoic acid)
5MH6 (NAD, 2‑ketohexanoic acid)
D4GTG1_HALVD ddh; 2-D-hydroxyacid dehydrogenase (EC:1.1.1.-) DDH Haloferax volcanii Archaea - - -
D4GYW8_HALVD serA1; phosphoglycerate dehydrogenase (EC:1.1.1.95) DDH Haloferax volcanii Archaea - - -
D4GV02_HALVD serA2; phosphoglycerate dehydrogenase (EC:1.1.1.95) DDH Haloferax volcanii Archaea - - -
D4GPR1_HALVD serA4; phosphoglycerate dehydrogenase DDH Haloferax volcanii Archaea - - -
B7G8Z0_PHATC 2-hydroxyacid dehydrogenase (EC:1.1.1.28) DDH Phaeodactylum tricornutum Eukaryotes - - -
B7FTZ9_PHATC hypothetical protein DDH Phaeodactylum tricornutum Eukaryotes - - -
Q93J73_STRCO SCBAC17F8.15; NAD-binding protein DDH Streptomyces coelicolor Bacteria - - -
FDH_ARATH FDH; formate dehydrogenase FDH Arabidopsis thaliana (thale cress) Eukaryotes formate formate 10.1016/S0176-1617(00)80186-8 3N7U (NAD, azide ion)
3JTM
3NAQ
ang:ANI_1_76134 An15g00410; formate dehydrogenase FDH Aspergillus niger Eukaryotes - - -
Q7VY50_BORPE formate dehydrogenase (EC:1.2.2.1) FDH Bordetella pertussis Tohama I Bacteria - - -
FDH_CANBO Formate dehydrogenase FDH Candida boidinii Eukaryotes formate formate PMID:27100912 2FSS PMID:17525463
2J6I PMID:17525463
A0A0A1EQY0_CANBO Formate dehydrogenase FDH Candida boidinii Eukaryotes - - - 5DN9 (NAD, azide ion) PMID:27100912
5DNA PMID:27100912
FDH_CHATD Formate dehydrogenase FDH Chaetomium thermophilum Eukaryotes formate formate 10.1016/j.molcatb.2015.09.014
G8NVB5_GRAMM Formate dehydrogenase FDH Granulicella mallensis Bacteria - - - 4XYB (NADP, azide ion) PMID:26104866
4XYE (NAD) PMID:26104866
4XYG PMID:26104866
Q5ZYS8_LEGPH formate dehydrogenase (EC:1.2.2.1) FDH Legionella pneumophila subsp. pneumophila Philadelphia 1 Bacteria - - -
O08375_MORSP Formate dehydrogenase FDH Moraxella sp. Bacteria - - - 2GSD (NAD, azide ion) PMID:19966418
3FN4 PMID:19966418
Q0DC43_ORYSJ Os06g0486800 FDH Oryza sativa japonica (Japanese rice) (RefSeq) Eukaryotes - - -
FDH2_ORYSJ Os06g0486900 FDH Oryza sativa japonica (Japanese rice) (RefSeq) Eukaryotes - - -
FDH_PSESR Formate dehydrogenase FDH Pseudomonas sp. Bacteria formate formate PMID:8484798 2GO1
2GUG (Formic acid)
2NAC PMID:8114093
2NAD (NAD, azide ion) PMID:8114093
FDH1_YEAST FDH1; formate dehydrogenase (NAD+) (EC:1.2.1.2) FDH Saccharomyces cerevisiae (budding yeast) Eukaryotes formate formate PMID:12144528
Q930E7_RHIME formate dehydrogenase (EC:1.2.2.1) FDH Sinorhizobium meliloti 1021 Bacteria - - -
sau:SA0171 fdh; formate dehydrogenase (EC:1.2.2.1) FDH Staphylococcus aureus subsp. aureus N315 (MRSA/VSSA) Bacteria - - -
Q76EB7_9PROT Formate dehydrogenase FDH Thiobacillus sp. KNK65MA Bacteria - - - 3WR5 (NAD)
Q7W075_BORPE 2-hydroxyacid dehydrogenase GHRA Bordetella pertussis Tohama I Bacteria - - -
Q7VWF3_BORPE 2-hydroxyacid dehydrogenase GHRA Bordetella pertussis Tohama I Bacteria - - -
Q8YED9_BRUME D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) GHRA Brucella melitensis bv. 1 16M Bacteria - - -
GHRA_ECOLI Glyoxylate/hydroxypyruvate reductase A GHRA Escherichia coli K-12 MG1655 Bacteria hydroxypyruvate, glyoxylate glyoxylate PMID:11237876
GHRA_KLEP7 ycdW; 2-ketoacid reductase GHRA Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Bacteria - - -
B5XVG7_KLEP3 2-ketoacid reductase GHRA Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Bacteria - - - 4N18
A8DWN5_NEMVE hypothetical protein GHRA Nematostella vectensis (sea anemone) Eukaryotes - - -
D4GHQ6_PANAM ycdW; YcdW GHRA Pantoea ananatis LMG 20103 Bacteria - - -
D4GCP9_PANAM ycdW; YcdW GHRA Pantoea ananatis LMG 20103 Bacteria - - -
Q8Y2S3_RALSO probable d-isomer specific 2-hydroxyacid dehydrogenase, nad-binding; oxidoreductase protein GHRA Ralstonia solanacearum GMI1000 Bacteria - - -
C1JH53_RHIET Glyoxylate reductase protein GHRA Rhizobium etli Bacteria phenylpyruvate, hydroxypyruvate, 2-ketobutyrate, glyoxylate glyoxylate PMID:17693143
Q2JYW0_RHIEC D-2-hydroxyacid dehydrogenase GHRA Rhizobium etli CFN 42 Bacteria - - -
Q2KDT2_RHIEC hydroxyacid dehydrogenase GHRA Rhizobium etli CFN 42 Bacteria - - - 5TSD (NADP, oxalic acid)
5BQF (NADP, tartaric acid)
4XCV (NADP)
Q3IWN8_RHOS4 2-hydroxyacid dehydrogenase GHRA Rhodobacter sphaeroides Bacteria - - - 4ZQB (NADP, sulfate ion)
5C5I
GHRA_SALTY 2-hydroxyacid dehydrogenase GHRA Salmonella enterica subsp. enterica serovar Typhi CT18 Bacteria - - - 3KBO (NADP)
3PP8
Q92Y74_RHIME dehydrogenase GHRA Sinorhizobium meliloti 1021 Bacteria - - -
Q92T34_RHIME hydroxyacid dehydrogenase (EC:1.1.1.-) GHRA Sinorhizobium meliloti 1021 Bacteria hydroxypyruvate, glyoxylate, pyruvate, hydroxyphenylpyruvate glyoxylate PMID:29309127 4WEQ (NADP, sulfate ion) PMID:29309127
4Z0P (NADP, oxalic acid) PMID:29309127
5UNN PMID:29309127
A7IIH0_XANP2 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding GHRA Xanthobacter autotrophicus Bacteria - - - 5VG6 (NADP, 2‑(N‑morpholino)‑ethanesulfonic acid (MES))
4XA8
Q5NLA3_ZYMMO D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein GHRA Zymomonas mobilis subsp. mobilis ZM4 Bacteria - - -
C7JFN2_ACEP3 D-isomer specific 2-hydroxyacid dehydrogenase GHRB Acetobacter pasteurianus IFO 3283-01 Bacteria - - -
acb:A1S_2248 2-keto-D-gluconate reductase GHRB Acinetobacter baumannii ATCC 17978 Bacteria - - -
HPR3_ARATH glyoxylate/hydroxypyruvate reductase HPR3 GHRB Arabidopsis thaliana (thale cress) Eukaryotes hydroxypyruvate, glyoxylate glyoxylate PMID:21205613
HPR1_ARATH HPR; hydroxypyruvate reductase GHRB Arabidopsis thaliana (thale cress) Eukaryotes hydroxypyruvate, glyoxylate hydroxypyruvate PMID:18952776
HPR2_ARATH glyoxylate/hydroxypyruvate reductase A HPR2 GHRB Arabidopsis thaliana (thale cress) Eukaryotes hydroxypyruvate, glyoxylate hydroxypyruvate PMID:18952776
A2Q988_ASPNC An01g07030; 2-hydroxyacid dehydrogenase UNK4.10 GHRB Aspergillus niger Eukaryotes - - -
A2QH07_ASPNC An03g05150; D-mandelate dehydrogenase GHRB Aspergillus niger Eukaryotes - - -
A2QU03_ASPNC An09g03890; 2-hydroxyacid dehydrogenase UNK4.10 GHRB Aspergillus niger Eukaryotes - - -
A2QX18_ASPNC An11g07270; 2-hydroxyacid dehydrogenase UNK4.10 GHRB Aspergillus niger Eukaryotes - - -
A2R1X3_ASPNC An13g02770; D-mandelate dehydrogenase GHRB Aspergillus niger Eukaryotes - - -
TKRA_BACSU yvcT; 2-ketogluconate reductase (EC:1.1.1.-) GHRB Bacillus subtilis subsp. subtilis 168 Bacteria - - -
Q7VTJ3_BORPE D-isomer specific 2-hydroxyacid dehydrogenase GHRB Bordetella pertussis Tohama I Bacteria - - -
bta:100337413 glyoxylate reductase/hydroxypyruvate reductase GHRB Bos taurus (cow) Eukaryotes - - -
F1MB84_BOVIN GRHPR; glyoxylate reductase/hydroxypyruvate reductase GHRB Bos taurus (cow) Eukaryotes - - -
G3N069_BOVIN uncharacterized LOC515578 GHRB Bos taurus (cow) Eukaryotes - - -
Q8YEC6_BRUME 2-hydroxyacid dehydrogenase (EC:1.1.1.215) GHRB Brucella melitensis bv. 1 16M Bacteria - - -
Q8YD64_BRUME glycerate dehydrogenase (EC:1.1.1.215) GHRB Brucella melitensis bv. 1 16M Bacteria - - -
bma:BMA0513 2-hydroxyacid dehydrogenase GHRB Burkholderia mallei ATCC 23344 Bacteria - - -
A0A0H2WC66_BURMA 2-hydroxyacid dehydrogenase GHRB Burkholderia mallei ATCC 23344 Bacteria - - -
GYAR_KORCO glyoxylate reductase (EC:1.1.1.26) GHRB Candidatus Korarchaeum cryptofilum Archaea - - -
DHGY_CUCSA Glycerate dehydrogenase GHRB Cucumis sativus (cucumber) Eukaryotes hydroxypyruvate, glyoxylate hydroxypyruvate PMID:16663015
B1WSC2_CYAA5 D-isomer specific 2-hydroxyacid dehydrogenase GHRB Cyanothece sp. ATCC 51142 Bacteria - - -
Q504F9_DANRE grhpra, grhpr, si:ch211-240l14.3, zgc:109900; glyoxylate reductase/hydroxypyruvate reductase a (EC:1.1.1.79) GHRB Danio rerio (zebrafish) Eukaryotes - - -
Q6P0V7_DANRE grhprb, fb80f04, wu:fb80f04, zgc:77636; glyoxylate reductase/hydroxypyruvate reductase b GHRB Danio rerio (zebrafish) Eukaryotes - - -
Q1JPX9_DANRE im:7137941; zgc:136493 GHRB Danio rerio (zebrafish) Eukaryotes - - -
D3PA38_DEFDS D-isomer specific 2-hydroxyacid dehydrogenase catalytic component GHRB Deferribacter desulfuricans Bacteria - - -
Q24Q83_DESHY hypothetical protein GHRB Desulfitobacterium hafniense Y51 Bacteria - - -
Q24WY0_DESHY hypothetical protein GHRB Desulfitobacterium hafniense Y51 Bacteria - - -
Q24RW1_DESHY hypothetical protein GHRB Desulfitobacterium hafniense Y51 Bacteria - - -
TKRA_DICDI tkrA; 2-keto-D-gluconate reductase GHRB Dictyostelium discoideum (cellular slime mold) Eukaryotes - - -
Q8I725_DROME CG1236 gene product from transcript CG1236-RA (EC:1.1.1.95) GHRB Drosophila melanogaster (fruit fly) Eukaryotes - - -
X2J9A5_DROME CG31673 gene product from transcript CG31673-RB (EC:1.1.1.79) GHRB Drosophila melanogaster (fruit fly) Eukaryotes - - -
Q8INU6_DROME CG31674 gene product from transcript CG31674-RA (EC:1.1.1.79) GHRB Drosophila melanogaster (fruit fly) Eukaryotes - - -
Q7KT11_DROME CG9331 gene product from transcript CG9331-RK (EC:1.1.1.-) GHRB Drosophila melanogaster (fruit fly) Eukaryotes - - -
GHRB_ECOLI ghrB; glyoxylate/hydroxypyruvate reductase B (EC:1.1.1.215 1.1.1.79) GHRB Escherichia coli K-12 MG1655 Bacteria hydroxypyruvate, 2-oxo-D-gluconate, glyoxylate hydroxypyruvate PMID:11237876
A5FIN4_FLAJ1 D-isomer specific 2-hydroxyacid dehydrogenase GHRB Flavobacterium johnsoniae Bacteria - - -
gga:426806 GRHPR; glyoxylate reductase/hydroxypyruvate reductase GHRB Gallus gallus (chicken) Eukaryotes - - -
gga:420808 probable 2-ketogluconate reductase-like GHRB Gallus gallus (chicken) Eukaryotes - - -
E1BRZ5_CHICK uncharacterized LOC420807 GHRB Gallus gallus (chicken) Eukaryotes - - -
Q5KVN6_GEOKA 2-hydroxyacid dehydrogenase GHRB Geobacillus kaustophilus Bacteria - - -
2KGR_GLUOX 2-ketogluconate reductase GHRB Gluconobacter oxydans 621H Bacteria 2-keto-D-gluconate, 2-keto-L-gulonate 2-keto-D-gluconate PMID:20676631
GRHPR_HUMAN GRHPR, GLXR, GLYD, PH2; glyoxylate reductase/hydroxypyruvate reductase (EC:1.1.1.79 1.1.1.81) GHRB Homo sapiens (human) Eukaryotes hydroxypyruvate, glyoxylate hydroxypyruvate PMID:16198644 2GCG (NADP; 2,3‑dihydroxypropanoic acid) PMID:16756993
2H1S
2Q50 PMID:17850744
2WWR PMID:16756993
DHGY_HYPME Glycerate dehydrogenase GHRB Hyphomicrobium methylovorum Bacteria hydroxypyruvate, glyoxylate hydroxypyruvate PMID:3830156 1GDH PMID:8120891
E3F052_KETVY D-2-hydroxyacid dehydrogensase protein GHRB Ketogulonicigenium vulgare Bacteria - - - 4LSW PMID:24068509
A6TI50_KLEP7 Phosphonate dehydrogenase (NAD-dependent phosphite dehydrogenase) GHRB Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Bacteria - - -
GHRB_KLEP7 tkrA; 2-hydroxyacid dehydrogenase GHRB Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Bacteria - - -
F9UM06_LACPL 2-hydroxyacid dehydrogenase GHRB Lactobacillus plantarum WCFS1 Bacteria - - -
Q5ZS40_LEGPH D-isomer specific 2-hydroxyacid dehydrogenase GHRB Legionella pneumophila subsp. pneumophila Philadelphia 1 Bacteria - - -
Q8YAN9_LISMO phosphoglycerate dehydrogenase GHRB Listeria monocytogenes EGD-e Bacteria - - -
Q3T9Z2_MOUSE Grhpr, 1110059D05Rik, 6430629L09Rik; glyoxylate reductase/hydroxypyruvate reductase (EC:1.1.1.79 1.1.1.81) GHRB Mus musculus (mouse) Eukaryotes - - -
A7RL06_NEMVE hypothetical protein GHRB Nematostella vectensis (sea anemone) Eukaryotes - - -
A7S382_NEMVE hypothetical protein GHRB Nematostella vectensis (sea anemone) Eukaryotes - - -
A7STU2_NEMVE hypothetical protein GHRB Nematostella vectensis (sea anemone) Eukaryotes - - -
A7RZX5_NEMVE hypothetical protein GHRB Nematostella vectensis (sea anemone) Eukaryotes - - -
A7STU0_NEMVE hypothetical protein GHRB Nematostella vectensis (sea anemone) Eukaryotes - - -
A9A5A9_NITMS glyoxylate reductase (EC:1.1.1.26) GHRB Nitrosopumilus maritimus Archaea - - -
Q8YK31_NOSS1 glycerate dehydrogenase GHRB Nostoc sp. PCC 7120 Bacteria - - -
Q8W0A4_ORYSJ Os01g0228600 GHRB Oryza sativa japonica (Japanese rice) (RefSeq) Eukaryotes - - -
Q6YU90_ORYSJ Os02g0101500 GHRB Oryza sativa japonica (Japanese rice) (RefSeq) Eukaryotes - - -
Q7X6P0_ORYSJ Os04g0106400 GHRB Oryza sativa japonica (Japanese rice) (RefSeq) Eukaryotes - - -
Q0JFF8_ORYSJ Os04g0107200 GHRB Oryza sativa japonica (Japanese rice) (RefSeq) Eukaryotes - - -
Q7XRA3_ORYSJ Os04g0107300 GHRB Oryza sativa japonica (Japanese rice) (RefSeq) Eukaryotes - - -
Q7XRA2_ORYSJ Os04g0107500 GHRB Oryza sativa japonica (Japanese rice) (RefSeq) Eukaryotes - - -
C6CWW4_PAESJ D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding GHRB Paenibacillus sp. JDR-2 Bacteria - - -
D4GFY0_PANAM tkrA; TkrA GHRB Pantoea ananatis LMG 20103 Bacteria - - -
HPPR_PLESU Hydroxyphenylpyruvate reductase GHRB Plectranthus scutellarioides Eukaryotes phenylpyruvate, 3,4-dihydroxyphenylpyruvate, 4-hydroxyphenylpyruvate 3,4-dihydroxyphenylpyruvate PMID:15284489 3BA1 PMID:20445235
3BAZ (NADP) PMID:20445235
Q120R1_POLSJ D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding GHRB Polaromonas sp. Bacteria - - - 4G2N
Q6A5K9_PROAC D-isomer specific 2-hydroxyacid dehydrogenase, putative D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) GHRB Propionibacterium acnes KPA171202 Bacteria - - -
G3XCL1_PSEAI 2-hydroxyacid dehydrogenase GHRB Pseudomonas aeruginosa PAO1 Bacteria - - -
Q9HXB7_PSEAE 2-hydroxyacid dehydrogenase GHRB Pseudomonas aeruginosa PAO1 Bacteria - - -
PTXD_PSEST Phosphonate dehydrogenase GHRB Pseudomonas stutzeri Bacteria phosphonate, hydroxypyruvate phosphonate PMID:11278981 4E5K (NAD, sulfite ion) PMID:22564171
4E5M (NADP) PMID:22564171
4E5N (NAD) PMID:22564171
4E5P (NAD) PMID:22564171
4EBF (NAD) PMID:22564171
4NU5 (NAD) PMID:24498026
4NU6 (NAD, sulfate ion) PMID:24498026
Q8ZXX8_PYRAE D-3-phosphoglycerate dehydrogenase GHRB Pyrobaculum aerophilum Archaea - - -
GYAR_PYRFU Glyoxylate reductase GHRB Pyrococcus furiosus Archaea - - - 5AOV (NADP, glyoxylic acid) PMID:26865263
GYAR_PYRHO PH0597; 376aa long hypothetical dehydrogenase GHRB Pyrococcus horikoshii Archaea hydroxypyruvate, glyoxylate hydroxypyruvate PMID:17327673 2DBQ (NADP, sulfate ion) PMID:17327673
2DBR (NADP, sulfate ion) PMID:17327673
2DBZ (NADP, sulfate ion) PMID:17327673
F8AEA4_PYRYC Glyoxylate reductase GHRB Pyrococcus yayanosii Archaea - - - 5AOW (NADP; 2,3‑dihydroxypropanoic acid) PMID:26865263
Q8Y0K9_RALSO hypothetical oxidoreductase protein (EC:1.1.-.-) GHRB Ralstonia solanacearum GMI1000 Bacteria - - -
Q8XRB3_RALSO probable dehydrogenase oxidoreductase protein (EC:1.1.-.-) GHRB Ralstonia solanacearum GMI1000 Bacteria - - -
Q8XSH1_RALSO putative d-3-phosphoglycerate dehydrogenase; oxidoreductase protein (EC:1.1.1.95) GHRB Ralstonia solanacearum GMI1000 Bacteria - - -
Q2K460_RHIEC 2-hydroxyacid dehydrogenase family protein GHRB Rhizobium etli CFN 42 Bacteria - - -
Q2KDX3_RHIEC D-2-hydroxyacid dehydrogenase GHRB Rhizobium etli CFN 42 Bacteria - - -
Q2K1I6_RHIEC D-2-hydroxyacid dehydrogensase GHRB Rhizobium etli CFN 42 Bacteria - - -
Q7LLW9_RHOGR D-mandelate dehydrogenase GHRB Rhodotorula graminis Eukaryotes D-mandalate, phenylglyoxylate D-mandalate 10.1099/00221287-135-7-2035, PMID:25449542 2W2L (NAD, sulfate ion)
2W2K
GOR1_YEAST GOR1; Gor1p (EC:1.1.1.26) GHRB Saccharomyces cerevisiae (budding yeast) Eukaryotes hydroxypyruvate, 2-hydroxyisocaproate, glyoxylate glyoxylate PMID:19681174
YP113_YEAST glyoxylate reductase (EC:1.-.-.-) GHRB Saccharomyces cerevisiae (budding yeast) Eukaryotes - - -
YGT5_YEAST putative hydroxyacid dehydrogenase (EC:1.-.-.-) GHRB Saccharomyces cerevisiae (budding yeast) Eukaryotes - - -
GHRB_SALTI yiaE; 2-hydroxyacid dehydrogenase GHRB Salmonella enterica subsp. enterica serovar Typhi CT18 Bacteria - - -
Q92MX8_RHIME 2-hydroxyacid dehydrogenase GHRB Sinorhizobium meliloti 1021 Bacteria - - -
Q92T15_RHIME 2-hydroxyacid dehydrogenase (EC:1.1.1.-) GHRB Sinorhizobium meliloti 1021 Bacteria - - -
Q930D0_RHIME D-isomer specific 2-hydroxyacid dehydrogenase GHRB Sinorhizobium meliloti 1021 Bacteria - - -
Q92XS7_RHIME dehydrogenase GHRB Sinorhizobium meliloti 1021 Bacteria - - -
Q92X49_RHIME dehydrogenase GHRB Sinorhizobium meliloti 1021 Bacteria - - -
Q92LZ4_RHIME glycerate dehydrogenase GHRB Sinorhizobium meliloti 1021 Bacteria glyoxylate, hydroxypyruvate, 2-keto-D-gluconate, hydroxyphenylpyruvate hydroxypyruvate PMID:29309127 5V7N (NADP, 2‑keto‑D‑gluconic acid) PMID:29309127
5J23 (2′‑monophosphoadenosine‑5′‑diphosphoribose (A2R)) PMID:29309127
5UOG PMID:29309127
5V6Q (NADP, malonic acid) PMID:29309127
5V72 PMID:29309127
5V7G (NADP, oxalate ion) PMID:29309127
Q931A1_RHIME Dehydrogenase GHRB Sinorhizobium meliloti 1021 Bacteria - - - 4DGS
sau:SA2098 glycerate dehydrogenase GHRB Staphylococcus aureus subsp. aureus N315 (MRSA/VSSA) Bacteria - - -
sau:SA0791 hypothetical protein GHRB Staphylococcus aureus subsp. aureus N315 (MRSA/VSSA) Bacteria - - -
GYAR_THEKO glyoxylate reductase (EC:1.1.1.26) GHRB Thermococcus kodakarensis Archaea - - -
GYAR_THELN Glyoxylate reductase GHRB Thermococcus litoralis Archaea hydroxypyruvate, phenylpyruvate, pyruvate, glyoxylate glyoxylate PMID:11532010
Q5SMG6_THET8 glycerate dehydrogenase/glyoxylate reductase GHRB Thermus thermophilus HB27 Bacteria - - - 2CUK
F1T2J9_9ASCO Phenylpyruvate reductase GHRB Wickerhamia fluorescens Eukaryotes hydroxypyruvate, pyruvate, 4-hydroxyphenylpyruvate, phenylpyruvate, glyoxylate, benzylformate, oxaloacetate phenylpyruvate PMID:21672638
Q8P7R1_XANCP 2-hydroxyacid dehydrogenase GHRB Xanthomonas campestris pv. campestris ATCC 33913 Bacteria - - -
A1L3E9_XENLA glyoxylate reductase/hydroxypyruvate reductase-like protein GHRB Xenopus laevis (African clawed frog) Eukaryotes - - -
Q6NTU8_XENLA grhpr.1, glxr, glyd; glyoxylate reductase/hydroxypyruvate reductase, gene 1 GHRB Xenopus laevis (African clawed frog) Eukaryotes - - -
Q498I1_XENLA grhpr.2; glyoxylate reductase/hydroxypyruvate reductase, gene 2 (EC:1.1.1.79) GHRB Xenopus laevis (African clawed frog) Eukaryotes - - -
A0A0B6NZT4_YERPE D-isomer specific 2-hydroxyacid dehydrogenase GHRB Yersinia pestis CO92 (biovar Orientalis) Bacteria - - -
A0A0B6NH52_YERPE D-isomer specific 2-hydroxyacid dehydrogenase family protein (EC:1.1.1.81) GHRB Yersinia pestis CO92 (biovar Orientalis) Bacteria - - -
Q5NR73_ZYMMO D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein GHRB Zymomonas mobilis subsp. mobilis ZM4 Bacteria - - -
Q8A8G0_BACTN glycerate dehydrogenase GHRC Bacteroides thetaiotaomicron Bacteria - - -
Q0PBD7_CAMJE 2-hydroxyacid dehydrogenase (EC:1.1.1.272) GHRC Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 Bacteria - - -
Q97F10_CLOAB glycerate dehydrogenase GHRC Clostridium acetobutylicum ATCC 824 Bacteria - - -
Q24YV7_DESHY hypothetical protein GHRC Desulfitobacterium hafniense Y51 Bacteria - - -
Q72C72_DESVH glycerate dehydrogenase GHRC Desulfovibrio vulgaris Hildenborough Bacteria - - - 5TX7
Q8REX0_FUSNN D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) GHRC Fusobacterium nucleatum subsp. nucleatum ATCC 25586 Bacteria - - -
Q74CK1_GEOSL hprA; hydroxypyruvate reductase GHRC Geobacter sulfurreducens PCA Bacteria - - -
Y1556_HAEIN glycerate dehydrogenase (EC:1.1.1.29) GHRC Haemophilus influenzae Rd KW20 (serotype d) Bacteria - - -
O24922_HELPY 2-hydroxyacid dehydrogenase (EC:1.1.1.272) GHRC Helicobacter pylori 26695 Bacteria - - -
Q03XJ7_LEUMM 2-hydroxyacid dehydrogenase GHRC Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Bacteria - - -
Q6LYW5_METMP glycerate dehydrogenase (EC:1.1.1.29) GHRC Methanococcus maripaludis S2 Archaea - - -
DHGY_METEA Glycerate dehydrogenase GHRC Methylobacterium extorquens Bacteria hydroxypyruvate, glyoxylate, glycerate hydroxypyruvate PMID:1657886
A0A0U1RH27_NEIMA glycerate dehydrogenase (EC:1.1.1.29) GHRC Neisseria meningitidis Z2491 (serogroup A) Bacteria - - -
D4GIZ2_PANAM hprA; HprA GHRC Pantoea ananatis LMG 20103 Bacteria - - -
D4GFK1_PANAM yiaE; YiaE GHRC Pantoea ananatis LMG 20103 Bacteria - - -
D5EYK0_PRER2 hprA; glycerate dehydrogenase (EC:1.1.1.29) GHRC Prevotella ruminicola Bacteria - - -
Q9HVG5_PSEAE hprA; glycerate dehydrogenase (EC:1.1.1.29) GHRC Pseudomonas aeruginosa PAO1 Bacteria - - -
Q9KP72_VIBCH D-lactate dehydrogenase GHRC Vibrio cholerae O1 biovar El Tor N16961 Bacteria - - -
X7PKE1_ECOLX - LDHD Escherichia coli O104:H4 Bacteria - - - 3WX0
D2RJU7_ACIFV D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein LDHD Acidaminococcus fermentans Bacteria - - - 1XDW
Q3M9R3_ANAVT D-lactate dehydrogenase (EC:1.1.1.28) LDHD Anabaena variabilis Bacteria - - -
A2QA09_ASPNC An01g09780; D-lactate dehydrogenase LDHD Aspergillus niger Eukaryotes - - -
Q8A7E9_BACTN D-lactate dehydrogenase LDHD Bacteroides thetaiotaomicron Bacteria - - -
A0A0H2WJ57_BURMA ldhA; D-lactate dehydrogenase (EC:1.1.1.28) LDHD Burkholderia mallei ATCC 23344 Bacteria - - -
B0LUZ5_CHLRE Putative D-lactate dehydrogenase LDHD Chlamydomonas reinhardtii Eukaryotes pyruvate, glyoxylate, lactate pyruvate PMID:26574578 4ZGS (NAD) PMID:26574578
Q97FN7_CLOAB D-lactate dehydrogenase LDHD Clostridium acetobutylicum ATCC 824 Bacteria - - -
Q97IU7_CLOAB lactate dehydrogenase LDHD Clostridium acetobutylicum ATCC 824 Bacteria - - -
B1WXW4_CYAA5 D-lactate dehydrogenase LDHD Cyanothece sp. ATCC 51142 Bacteria - - -
LDHD_DICDI ldhA; D-lactate dehydrogenase LDHD Dictyostelium discoideum (cellular slime mold) Eukaryotes - - -
VANH_ENTFA D-specific alpha-keto acid dehydrogenase LDHD Enterococcus faecalis V583 Bacteria - - -
VANH_ENTFC D-specific alpha-keto acid dehydrogenase LDHD Enterococcus faecium Bacteria 2-ketobutyrate, 2-ketovalerate, pyruvate, 2-ketoisocaproate, 2-ketocaproate, phenylpyruvate, 2-ketoisovalerate pyruvate PMID:1931965
LDHD_ECOLI D-lactate dehydrogenase LDHD Escherichia coli K-12 MG1655 Bacteria pyruvate pyruvate PMID:4297266, PMID:6393891 3WX0
A5FIM6_FLAJ1 D-isomer specific 2-hydroxyacid dehydrogenase LDHD Flavobacterium johnsoniae Bacteria - - -
Q8RG31_FUSNN D-lactate dehydrogenase (EC:1.1.99.2) LDHD Fusobacterium nucleatum subsp. nucleatum ATCC 25586 Bacteria - - -
Q8RG11_FUSNN D-lactate dehydrogenase LDHD Fusobacterium nucleatum subsp. nucleatum ATCC 25586 Bacteria - - - 3WWY
DDH_HAEIN ldhA; D-lactate dehydrogenase LDHD Haemophilus influenzae Rd KW20 (serotype d) Bacteria - - -
A6T8G0_KLEP7 ldhA; D-lactate dehydrogenase LDHD Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Bacteria - - -
Q03CR3_LACC3 (R)-2-hydroxyisocaproate dehydrogenase LDHD Lactobacillus casei ATCC 334 Bacteria 2-ketobutyrate, lactate, pyruvate, 4-hydroxyphenylpyruvate, phenylpyruvate, 2-oobutanoate, 2-oxovalerate, 2-oxohexanoate phenylpyruvate 10.1016/0141-0229(92)90022-G
Q1GAA2_LACDA D-isomer specific 2-hydroxyacid dehydrogenase LDHD Lactobacillus delbrueckii subsp. bulgaricus Bacteria - - - 2YQ4 PMID:23110853
2YQ5 (NAD) PMID:23110853
LDHD_LACDA D-lactate dehydrogenase LDHD Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 Bacteria 2-ketobutyrate, pyruvate, phenylpyruvate, glyoxylate, lactate, bromopyruvate, oxaloacetate pyruvate PMID:1569100 1J49 (NAD) PMID:12054772
1J4A PMID:12054772
LDHD_LACHE D-lactate dehydrogenase LDHD Lactobacillus helveticus Bacteria - - - 2DLD (NAD, oxamic acid)
C4VLM6_9LACO 4-phosphoerythronate dehydrogenase LDHD Lactobacillus jensenii 269-3 Bacteria - - - 4PRK
DHD2_LACPA D-2-hydroxyisocaproate dehydrogenase LDHD Lactobacillus paracasei Bacteria 2-keto-3-methylbutyrate, 2-keto-4-methylmercaptobutyrate, 2-ketobutyrate, 2-ketooctanoate, 2-ketovalerate, mercaptopyruvate, 2-ketoisocaproate, phenylpyruvate, 2-ketocaproate, 2-keto-3-methylvalerate 2-ketoisocaproate 10.1007/BF00252354 1DXY (NAD, 2‑oxo‑4‑methylpentanoic acid) PMID:9126843
LDHD_LACPE D-lactate dehydrogenase LDHD Lactobacillus pentosus Bacteria hydroxypyruvate, 2-ketobutyrate, 2-ketovalerate, pyruvate, 2-ketoisocaproate, 2-ketocaproate, phenylpyruvate, 2-ketoisovalerate pyruvate PMID:12897026
LDHD_LACPL ldhD; D-lactate dehydrogenase LDHD Lactobacillus plantarum WCFS1 Bacteria hydroxypyruvate, 2-ketobutyrate, 2-ketovalerate, pyruvate, 2-ketoisocaproate, 2-ketocaproate, phenylpyruvate, 2-ketoisovalerate pyruvate PMID:1840590
F9UM82_LACPL bifunctional protein: aminotransferase (pyridoxal-phosphate-dependent); 2-hydroxyacid dehydrogenase LDHD Lactobacillus plantarum WCFS1 Bacteria - - -
LDHD_LEUMC D-lactate dehydrogenase, LdhA LDHD Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Bacteria phenylpyruvate, pyruvate, 2-ketobutyrate pyruvate PMID:1931965
Q03UK9_LEUMM lactate dehydrogenase LDHD Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Bacteria - - -
Q03Z77_LEUMM lactate dehydrogenase related 2-hydroxyacid dehydrogenase LDHD Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Bacteria - - -
Q03V58_LEUMM lactate dehydrogenase related 2-hydroxyacid dehydrogenase LDHD Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Bacteria - - -
Q1CWE5_MYXXD ldhA; D-lactate dehydrogenase (EC:1.1.1.28) LDHD Myxococcus xanthus Bacteria - - -
A0A0U1RK09_NEIMA D-lactate dehydrogenase (EC:1.1.1.28) LDHD Neisseria meningitidis Z2491 (serogroup A) Bacteria - - -
Q8Z0N3_NOSS1 D-lactate dehydrogenase LDHD Nostoc sp. PCC 7120 Bacteria - - -
D4GF56_PANAM ldhA; LdhA LDHD Pantoea ananatis LMG 20103 Bacteria - - -
B7S4E4_PHATC 2-hydroxyacid dehydrogenase LDHD Phaeodactylum tricornutum Eukaryotes - - -
Q9I530_PSEAE ldhA; D-lactate dehydrogenase LDHD Pseudomonas aeruginosa PAO1 Bacteria - - - 3WWZ
Q8XUQ5_RALSO ldhA; putative d-lactate dehydrogenase (d-ldh) oxidoreductase protein (EC:1.1.1.28) LDHD Ralstonia solanacearum GMI1000 Bacteria - - -
Q8Z780_SALTI D-lactate dehydrogenase LDHD Salmonella enterica subsp. enterica serovar Typhi CT18 Bacteria - - - 4CUK (NAD)
4CUJ
A0A0M3KL04_9BACL D-lactate dehydrogenase LDHD Sporolactobacillus inulinus CASD Bacteria - - - 4XKJ (NAD)
sau:SA2346 D-lactate dehydrogenase (EC:1.1.1.28) LDHD Staphylococcus aureus subsp. aureus N315 (MRSA/VSSA) Bacteria - - -
sau:SA2312 ddh; D-lactate dehydrogenase (EC:1.1.1.28) LDHD Staphylococcus aureus subsp. aureus N315 (MRSA/VSSA) Bacteria - - -
LDHD_STRP1 ddh; D-lactate dehydrogenase (EC:1.1.1.28) LDHD Streptococcus pyogenes SF370 (serotype M1) Bacteria - - -
Q9XAK8_STRCO dldh, SC66T3.05; D-lactate dehydrogenase LDHD Streptomyces coelicolor Bacteria - - -
Q9S2M5_STRCO dldh2, SCE10.12c; D-lactate dehydrogenase LDHD Streptomyces coelicolor Bacteria - - -
syn:slr1556 ddh; D-lactate dehydrogenase LDHD Synechocystis sp. PCC 6803 Bacteria - - -
LDHD_TREPA D-specific D-2-hydroxyacid dehydrogenase LDHD Treponema pallidum subsp. pallidum Nichols Bacteria - - -
Q9KMX4_VIBCH D-lactate dehydrogenase LDHD Vibrio cholerae O1 biovar El Tor N16961 Bacteria - - -
A0A0B6P5V7_YERPE hslI; D-lactate dehydrogenase (EC:1.1.1.28) LDHD Yersinia pestis CO92 (biovar Orientalis) Bacteria - - -
DDH_ZYMMO D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein LDHD Zymomonas mobilis subsp. mobilis ZM4 Bacteria - - -
acb:A1S_2637 erythronate-4-phosphate dehydrogenase PDXB Acinetobacter baumannii ATCC 17978 Bacteria - - -
PDXB_BACTN erythronate-4-phosphate dehydrogenase PDXB Bacteroides thetaiotaomicron Bacteria - - -
PDXB_ECOLI pdxB; erythronate-4-phosphate dehydrogenase (EC:1.1.1.-) PDXB Escherichia coli K-12 MG1655 Bacteria alpha-ketoglutarate, pyruvate, 4-phospho-D-erythronate, oxaloacetate 4-phospho-D-erythronate PMID:20831184
A6TC06_KLEP7 pdxB; erythronate-4-phosphate dehydrogenase PDXB Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Bacteria - - -
PDXB_LEGPH erythronate-4-phosphate dehydrogenase (EC:1.1.1.-) PDXB Legionella pneumophila subsp. pneumophila Philadelphia 1 Bacteria - - -
D4GJ89_PANAM pdxB; PdxB PDXB Pantoea ananatis LMG 20103 Bacteria - - -
PDXB_PSEAE pdxB; erythronate-4-phosphate dehydrogenase PDXB Pseudomonas aeruginosa PAO1 Bacteria - - - 2O4C (NAD, tartaric acid) PMID:17217963
PDXB_SALTY pdxB; erythronate-4-phosphate dehydrogenase (EC:1.1.1.-) PDXB Salmonella enterica subsp. enterica serovar Typhi CT18 Bacteria - - - 3OET (NAD)
PDXB_SODGM erythronate-4-phosphate dehydrogenase PDXB Sodalis glossinidius (Glossina spp.) Bacteria - - -
PDXB_VIBCH erythronate-4-phosphate dehydrogenase PDXB Vibrio cholerae O1 biovar El Tor N16961 Bacteria - - - 5DT9 (NAD)
A0A0B6NWJ3_YERPE pdxB; D-isomer specific 2-hydroxyacid dehydrogenase PDXB Yersinia pestis CO92 (biovar Orientalis) Bacteria - - -
C7JH84_ACEP3 D-3-phosphoglycerate dehydrogenase SERA Acetobacter pasteurianus IFO 3283-01 Bacteria - - -
Q3M6M2_ANAVT D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Anabaena variabilis Bacteria - - -
O67741_AQUAE serA; D-3-phosphoglycerate dehydrogenase SERA Aquifex aeolicus Bacteria - - -
SERA2_ARATH D-3-phosphoglycerate dehydrogenase SERA Arabidopsis thaliana (thale cress) Eukaryotes 3-phosphoglycerate 3-phosphoglycerate PMID:24368794
SERA3_ARATH D-3-phosphoglycerate dehydrogenase SERA Arabidopsis thaliana (thale cress) Eukaryotes 3-phosphoglycerate 3-phosphoglycerate PMID:24368794
SERA1_ARATH EDA9; D-3-phosphoglycerate dehydrogenase SERA Arabidopsis thaliana (thale cress) Eukaryotes - - -
SERA_ARCFU phosphoglycerate dehydrogenase (serA) SERA Archaeoglobus fulgidus DSM 4304 Archaea - - -
A2QYK6_ASPNC An12g01580; D-3-phosphoglycerate dehydrogenase SERA Aspergillus niger Eukaryotes - - -
ang:ANI_1_348154 An17g02330; D-3-phosphoglycerate dehydrogenase 1 SERA Aspergillus niger Eukaryotes - - -
SERA_BACSU serA; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Bacillus subtilis subsp. subtilis 168 Bacteria - - -
Q8A8L5_BACTN D-3-phosphoglycerate dehydrogenase SERA Bacteroides thetaiotaomicron Bacteria - - -
Q8G4R3_BIFLO serA; D-3-phosphoglycerate dehydrogenase SERA Bifidobacterium longum NCC2705 Bacteria - - -
Q7W0H7_BORPE serA; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Bordetella pertussis Tohama I Bacteria - - -
SERA_BOVIN PHGHRC; phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Bos taurus (cow) Eukaryotes - - -
Q2YK82_BRUA2 Amino acid-binding ACT:D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain:D-isomer specific 2-hydroxyacid dehydrogenase SERA Brucella abortus Bacteria - - - 3K5P
Q8YIU3_BRUME D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Brucella melitensis bv. 1 16M Bacteria - - -
Q8YBS3_BRUME D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Brucella melitensis bv. 1 16M Bacteria - - -
O17626_CAEEL C31C9.2; Uncharacterized protein SERA Caenorhabditis elegans (nematode) Eukaryotes - - -
Q0PA07_CAMJE serA; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 Bacteria - - -
Q3AQU0_CHLCH D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Chlorobium chlorochromatii Bacteria - - -
SLCC_CHRSD (S)-sulfolactate dehydrogenase SERA Chromohalobacter salexigens Bacteria 3-sulfopyruvate, sulfolactate sulfolactate PMID:20007648
Q97N23_CLOAB serA; D-3-phosphoglycerate dehydrogenase SERA Clostridium acetobutylicum ATCC 824 Bacteria - - -
Q8NQY7_CORGL Cgl1284; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Corynebacterium glutamicum ATCC 13032 (Kyowa Hakko) Bacteria - - -
B1WNQ5_CYAA5 serA; D-3-phosphoglycerate dehydrogenase SERA Cyanothece sp. ATCC 51142 Bacteria - - -
F1QEY8_DANRE phGHRC, fb38f06, wu:fb38f06, zgc:65956; phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Danio rerio (zebrafish) Eukaryotes - - -
D3PCL0_DEFDS serA; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Deferribacter desulfuricans Bacteria - - -
Q3Z8V8_DEHM1 serA; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Dehalococcoides mccartyi 195 Bacteria - - -
Q9RUU0_DEIRA D-3-phosphoglycerate dehydrogenase SERA Deinococcus radiodurans Bacteria - - -
Q24YY4_DESHY hypothetical protein SERA Desulfitobacterium hafniense Y51 Bacteria - - -
Q24NC0_DESHY hypothetical protein SERA Desulfitobacterium hafniense Y51 Bacteria - - -
SERA_DICDI serA; 3-phosphoglycerate dehydrogenase SERA Dictyostelium discoideum (cellular slime mold) Eukaryotes - - -
Q9VKI8_DROME CG6287 gene product from transcript CG6287-RA (EC:1.1.1.95) SERA Drosophila melanogaster (fruit fly) Eukaryotes - - -
B2KCL9_ELUMP putative phosphoglycerate dehydrogenase SERA Elusimicrobium minutum Bacteria - - -
Q76KF5_ENTHI D-3-phosphoglycerate dehydrogenase, putative SERA Entamoeba histolytica Eukaryotes 3-phosphoglycerate 3-phosphoglycerate PMID:25294608 4NJO (NAD, formic acid) PMID:25294608
4NFY PMID:25294608
4NJM (3‑phosphoglyceric acid) PMID:25294608
SERA_ECOLI D-3-phosphoglycerate dehydrogenase SERA Escherichia coli K-12 MG1655 Bacteria 3-phosphoglycerate, 2-ketoglutarate 3-phosphoglycerate PMID:15668250 1YBA (NAD, 2‑oxoglutaric acid) PMID:15823035
1PSD (NAD) PMID:7719856
1SC6 (NAD) PMID:15035616
2P9C (NAD) PMID:17459882
2P9E (NAD) PMID:17459882
2P9G (NAD) PMID:17459882
2PA3 (NAD) PMID:17459882
A5FH27_FLAJ1 D-isomer specific 2-hydroxyacid dehydrogenase SERA Flavobacterium johnsoniae Bacteria - - -
E1C7Y3_CHICK PHGHRC; phosphoglycerate dehydrogenase SERA Gallus gallus (chicken) Eukaryotes - - -
Q5KXQ4_GEOKA phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Geobacillus kaustophilus Bacteria - - -
Q74DW7_GEOSL serA; D-3-phosphoglycerate dehydrogenase SERA Geobacter sulfurreducens PCA Bacteria - - -
SERA_HAEIN serA; D-3-phosphoglycerate dehydrogenase SERA Haemophilus influenzae Rd KW20 (serotype d) Bacteria - - -
Q5UZ36_HALMA serA1; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Haloarcula marismortui Archaea - - -
D4GY36_HALVD serA3; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Haloferax volcanii Archaea - - -
O25158_HELPY D-3-phosphoglycerate dehydrogenase SERA Helicobacter pylori 26695 Bacteria - - -
SERA_HUMAN PHGHRC, 3-PGHRC, 3PGHRC, HEL-S-113, NLS, NLS1, PDG, PGAD, PGD, PGHRC, PHGHRCD, SERA; phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Homo sapiens (human) Eukaryotes - - - 2G76 (NAD, malate ion)
5N53 ((3‑chloranyl‑4‑methoxy‑phenyl)ethanamide (8NB)) PMID:27564259
A6TDS4_KLEP7 serA; D-3-phosphoglycerate dehydrogenase SERA Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Bacteria - - -
F9UT10_LACPL serA; D-3-phosphoglycerate dehydrogenase SERA Lactobacillus plantarum WCFS1 Bacteria - - -
Q9CHW4_LACLA serA; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Lactococcus lactis subsp. lactis Il1403 Bacteria - - -
Q03W66_LEUMM D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Bacteria - - -
Q8Y3L1_LISMO D-3-phosphoglycerate dehydrogenase SERA Listeria monocytogenes EGD-e Bacteria - - -
Q6LWW6_METMP serA; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Methanococcus maripaludis S2 Archaea - - -
B0JX04_MICAN serA; D-3-phosphoglycerate dehydrogenase SERA Microcystis aeruginosa Bacteria - - -
SERA_MOUSE PhGHRC, 3-PGHRC, 3PGHRC, 4930479N23, A10, PGAD, PGD, PGHRC, SERA; 3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Mus musculus (mouse) Eukaryotes - - -
SERA_MYCTU serA1; D-3-phosphoglycerate dehydrogenase SERA Mycobacterium tuberculosis H37Rv Bacteria 3-phosphoglycerate 3-phosphoglycerate PMID:15668250 1YGY PMID:15668249
3DC2 PMID:18627175
3DDN PMID:18627175
Q1CYP3_MYXXD serA; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Myxococcus xanthus Bacteria - - -
A7SFV8_NEMVE hypothetical protein SERA Nematostella vectensis (sea anemone) Eukaryotes - - -
A9A1H5_NITMS NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase SERA Nitrosopumilus maritimus Archaea - - -
Q8YVT4_NOSS1 phosphoglycerate dehydrogenase SERA Nostoc sp. PCC 7120 Bacteria - - -
Q7XMP6_ORYSJ Os04g0650800 SERA Oryza sativa japonica (Japanese rice) (RefSeq) Eukaryotes - - -
Q0DAG1_ORYSJ Os06g0655100 SERA Oryza sativa japonica (Japanese rice) (RefSeq) Eukaryotes - - -
C6CU86_PAESJ D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Paenibacillus sp. JDR-2 Bacteria - - -
D4GM95_PANAM serA; SerA SERA Pantoea ananatis LMG 20103 Bacteria - - -
B7FY72_PHATC 2-hydroxyacid dehydrogenase (EC:1.1.1.95) SERA Phaeodactylum tricornutum Eukaryotes - - -
B7FY73_PHATC hypothetical protein SERA Phaeodactylum tricornutum Eukaryotes - - -
D5ERW2_PRER2 serA; D-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Prevotella ruminicola Bacteria - - -
Q7VAM4_PROMA serA; D-3-phosphoglycerate dehydrogenase SERA Prochlorococcus marinus SS120 Bacteria - - -
Q6A895_PROAC D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Propionibacterium acnes KPA171202 Bacteria - - -
Q9I6H5_PSEAE serA; D-3-phosphoglycerate dehydrogenase SERA Pseudomonas aeruginosa PAO1 Bacteria - - -
Q8ZTC7_PYRAE D-3-phosphoglycerate dehydrogenase SERA Pyrobaculum aerophilum Archaea - - -
O50095_PYRHO 307aa long hypothetical phosphoglycerate dehydrogenase SERA Pyrococcus horikoshii Archaea - - - 1WWK (NAD)
Q2K4M6_RHIEC serA; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Rhizobium etli CFN 42 Bacteria - - -
SER33_YEAST SER33; phosphoglycerate dehydrogenase SER33 (EC:1.1.1.95) SERA Saccharomyces cerevisiae (budding yeast) Eukaryotes 3-phosphoglycerate 3-phosphoglycerate PMID:12525494
SERA_YEAST SER3; phosphoglycerate dehydrogenase SER3 (EC:1.1.1.95) SERA Saccharomyces cerevisiae (budding yeast) Eukaryotes 3-phosphoglycerate 3-phosphoglycerate PMID:12525494
Q8Z3W3_SALTI serA; D-3-phosphoglycerate dehydrogenase SERA Salmonella enterica subsp. enterica serovar Typhi CT18 Bacteria - - -
Q92MA3_RHIME serA; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Sinorhizobium meliloti 1021 Bacteria - - -
Q2NRE1_SODGM D-3-phosphoglycerate dehydrogenase SERA Sodalis glossinidius (Glossina spp.) Bacteria - - -
sau:SA1545 serA; D-3-phosphoglycerate dehydrogenase SERA Staphylococcus aureus subsp. aureus N315 (MRSA/VSSA) Bacteria - - -
Q9Z564_STRCO SC8D9.27, serA; D-3-phosphoglycerate dehydrogenase SERA Streptomyces coelicolor Bacteria - - -
Q97ZK1_SULSO serA-1; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Sulfolobus solfataricus P2 Archaea - - -
Q972A9_SULTO D-3-phosphoglycerate dehydrogenase SERA Sulfolobus tokodaii Archaea - - - 2EKL (NAD)
Q7U8S8_SYNPX serA; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Synechococcus sp. WH8102 Bacteria - - -
syn:sll1908 serA; D-3-phosphoglycerate dehydrogenase SERA Synechocystis sp. PCC 6803 Bacteria - - -
Q5JGC4_THEKO D-3-phosphoglycerate dehydrogenase SERA Thermococcus kodakarensis Archaea - - -
B5YKK8_THEYD serA; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Thermodesulfovibrio yellowstonii Bacteria - - -
HPR_THEMA D-3-phosphoglycerate dehydrogenase SERA Thermotoga maritima MSB8 Bacteria - - -
Q9WYG2_THEMA phosphoglycerate dehydrogenase SERA Thermotoga maritima MSB8 Bacteria - - -
Q72K32_THET2 D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Thermus thermophilus HB27 Bacteria - - -
Q9KP92_VIBCH D-3-phosphoglycerate dehydrogenase SERA Vibrio cholerae O1 biovar El Tor N16961 Bacteria - - -
Q8P9M8_XANCP serA; D-3-phosphoglycerate dehydrogenase SERA Xanthomonas campestris pv. campestris ATCC 33913 Bacteria - - -
A1L3N1_XENLA phGHRC; phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Xenopus laevis (African clawed frog) Eukaryotes - - -
A0A0B6NXZ1_YERPE serA; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) SERA Yersinia pestis CO92 (biovar Orientalis) Bacteria - - -
Q5NLV1_ZYMMO D-3-phosphoglycerate dehydrogenase SERA Zymomonas mobilis subsp. mobilis ZM4 Bacteria - - -
D0JAW6_BLASB serA; phosphoglycerate dehydrogenase (EC:1.1.1.95) X1 Blattabacterium Bge (Blattella germanica) Bacteria - - -
A5FLN9_FLAJ1 D-isomer specific 2-hydroxyacid dehydrogenase X1 Flavobacterium johnsoniae Bacteria - - -
Q03WU1_LEUMM lactate dehydrogenase related dehydrogenase X1 Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Bacteria - - -
Q03Z11_LEUMM lactate dehydrogenase-like protein X1 Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Bacteria - - -
Q03YV3_LEUMM lactate dehydrogenase-like protein X1 Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Bacteria - - -
A2QVH2_ASPNC An11g01390; D-isomer specific 2-hydroxyacid dehydrogenase family protein X10 Aspergillus niger Eukaryotes - - -
Q7VU57_BORPE 2-hydroxyacid dehydrogenase X10 Bordetella pertussis Tohama I Bacteria - - -
A0A0H2WGR7_BURMA glyoxylate reductase X10 Burkholderia mallei ATCC 23344 Bacteria - - -
C6D035_PAESJ D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding X10 Paenibacillus sp. JDR-2 Bacteria - - -
D4GCV1_PANAM gyaR; GyaR X10 Pantoea ananatis LMG 20103 Bacteria - - -
Q8Y3G4_RALSO Putative d-3-phosphoglycerate dehydrogenase oxidoreductase protein X10 Ralstonia solanacearum GMI1000 Bacteria - - - 3GG9
Q9KYH6_STRCO SCC61A.17; 2-hydroxyacid dehydrogenase X10 Streptomyces coelicolor Bacteria - - -
A0A0H3ADB2_VIBC3 D-3-phosphoglycerate dehydrogenase X10 Vibrio cholerae O1 biovar El Tor N16961 Bacteria - - - 4S1V
Q8PEG0_XANCP serA; D-3-phosphoglycerate dehydrogenase X10 Xanthomonas campestris pv. campestris ATCC 33913 Bacteria - - -
Q5KYJ7_GEOKA dehydrogenase X11 Geobacillus kaustophilus Bacteria - - -
Q5V1E2_HALMA serA2; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) X11 Haloarcula marismortui Archaea - - -
Q5V0P1_HALMA serA3; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) X11 Haloarcula marismortui Archaea - - -
Q9RKF9_STRCO SCE65.14c; dehydrogenase X11 Streptomyces coelicolor Bacteria - - -
Q7CHE1_YERPE D-isomer specific 2-hydroxyacid dehydrogenase family protein X11 Yersinia pestis CO92 (biovar Orientalis) Bacteria - - -
F4IBQ3_ARATH D-isomer specific 2-hydroxyacid dehydrogenase domain protein ARA X12 Arabidopsis thaliana (thale cress) Eukaryotes - - -
ang:ANI_1_2068074 An08g06710; D-isomer specific 2-hydroxyacid dehydrogenase family protein X12 Aspergillus niger Eukaryotes - - -
Q82ZC3_ENTFA D-isomer specific 2-hydroxyacid dehydrogenase family protein X12 Enterococcus faecalis V583 Bacteria - - -
Q0D7C9_ORYSJ Os07g0264100 X12 Oryza sativa japonica (Japanese rice) (RefSeq) Eukaryotes - - -
B7FWQ5_PHATC hypothetical protein X12 Phaeodactylum tricornutum Eukaryotes - - -
O58256_PYRHO 333aa long hypothetical dehydrogenase X12 Pyrococcus horikoshii Archaea - - - 2D0I
Q5JF48_THEKO 2-hydroxyacid dehydrogenase X12 Thermococcus kodakarensis Archaea - - -
Q2K273_RHIEC Probable phosphoglycerate oxidoreductase protein X13 Rhizobium etli CFN 42 Bacteria - - - 4HY3
Q92SV1_RHIME oxidoreductase X13 Sinorhizobium meliloti 1021 Bacteria - - -
syn:slr2123 D-isomer specific 2-hydroxyacid dehydrogenase X13 Synechocystis sp. PCC 6803 Bacteria - - -
YOAD_BACSU yoaD; 2-hydroxyacid dehydrogenase YoaD (EC:1.1.1.-) X2 Bacillus subtilis subsp. subtilis 168 Bacteria - - -
Q72F75_DESVH D-isomer specific 2-hydroxyacid dehydrogenase X2 Desulfovibrio vulgaris Hildenborough Bacteria - - -
A6T665_KLEP7 putative D-3-phosphoglycerate dehydrogenase X2 Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Bacteria - - -
I6WZ71_MYCTU serA2; D-3-phosphoglycerate dehydrogenase SerA X2 Mycobacterium tuberculosis H37Rv Bacteria - - -
D4GKT0_PANAM serA; SerA X2 Pantoea ananatis LMG 20103 Bacteria - - -
Q2JYR7_RHIEC phosphoglycerate dehydrogenase (EC:1.1.1.95) X2 Rhizobium etli CFN 42 Bacteria - - -
Q92YX6_RHIME dehydrogenase X2 Sinorhizobium meliloti 1021 Bacteria - - -
Q92NH1_RHIME oxidoreductase X2 Sinorhizobium meliloti 1021 Bacteria - - -
Q92MQ6_RHIME oxidoreductase (EC:1.-.-.-) X2 Sinorhizobium meliloti 1021 Bacteria - - -
Q2KE34_RHIEC D-2-hydroxyacid dehydrogenase X3 Rhizobium etli CFN 42 Bacteria - - -
Q92W31_RHIME dehydrogenase X3 Sinorhizobium meliloti 1021 Bacteria - - -
Q9RJW2_STRCO SCF41.07; 2-hydroxyacid dehydrogenase X3 Streptomyces coelicolor Bacteria - - -
Q9RJA1_STRCO SCF91.23; 2-hydroxyacid dehydrogenase X3 Streptomyces coelicolor Bacteria - - -
Q8ZXP5_PYRAE 2-hydroxyacid dehydrogenase X4 Pyrobaculum aerophilum Archaea - - - 1QP8 (NADP)
Q97U35_SULSO serA-2; D-3-phosphoglycerate dehydrogenase, (serA-2) (EC:1.1.1.95) X4 Sulfolobus solfataricus P2 Archaea - - -
Q9HJV5_THEAC Glycerate dehydrogenase related protein X4 Thermoplasma acidophilum Archaea - - - 3GVX
Q8NU69_CORGL Cgl0070; phosphoglycerate dehydrogenase or related dehydrogenase X5 Corynebacterium glutamicum ATCC 13032 (Kyowa Hakko) Bacteria - - -
Y2355_CORGL Cgl2355; phosphoglycerate dehydrogenase X5 Corynebacterium glutamicum ATCC 13032 (Kyowa Hakko) Bacteria - - -
Q9RTQ5_DEIRA 2-hydroxyacid dehydrogenase X5 Deinococcus radiodurans Bacteria - - -
Q9FC67_STRCO SC4B10.20; dehydrogenase X5 Streptomyces coelicolor Bacteria - - -
Q9Z569_STRCO SC8D9.22; dehydrogenase X5 Streptomyces coelicolor Bacteria - - -
A4SIK7_AERS4 D-isomer specific 2-hydroxyacid dehydrogenase family protein X6 Aeromonas salmonicida Bacteria - - - 3HG7
Q9I448_PSEAE 2-hydroxyacid dehydrogenase X6 Pseudomonas aeruginosa PAO1 Bacteria - - -
Q9KV89_VIBCH D-isomer specific 2-hydroxyacid dehydrogenase family protein X6 Vibrio cholerae O1 biovar El Tor N16961 Bacteria - - -
Q8G843_BIFLO hypothetical protein X7 Bifidobacterium longum NCC2705 Bacteria - - -
Q97M35_CLOAB phosphoglycerate dehydrogenase X7 Clostridium acetobutylicum ATCC 824 Bacteria - - -
Q82ZZ6_ENTFA D-isomer specific 2-hydroxyacid dehydrogenase family protein X7 Enterococcus faecalis V583 Bacteria - - -
F9URQ7_LACPL 2-hydroxyacid dehydrogenase X7 Lactobacillus plantarum WCFS1 Bacteria - - - 3EVT
Q9CE59_LACLA yugC; dehydrogenase X7 Lactococcus lactis subsp. lactis Il1403 Bacteria - - -
Q03WK8_LEUMM phosphoglycerate dehydrogenase-like protein X7 Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Bacteria - - -
Q8Y6K0_LISMO glycerate dehydrogenase X7 Listeria monocytogenes EGD-e Bacteria - - -
sau:SA1679 hypothetical protein X7 Staphylococcus aureus subsp. aureus N315 (MRSA/VSSA) Bacteria - - -
Q97MV2_CLOAB serA; D-2-hydroxyacid dehydrogenase X8 Clostridium acetobutylicum ATCC 824 Bacteria - - -
Q5ZYW9_LEGPH serA; D-3-phosphoglycerate dehydrogenase (EC:1.1.1.95) X8 Legionella pneumophila subsp. pneumophila Philadelphia 1 Bacteria - - -
O66939_AQUAE ldhA; D-lactate dehydrogenase X9 Aquifex aeolicus Bacteria - - - 3KB6 (NAD, lactic acid) PMID:20054113
B2KDH0_ELUMP putative lactate dehydrogenase X9 Elusimicrobium minutum Bacteria - - -